WebApr 1, 2024 · Human relaxin-2 (H2 relaxin) is therapeutically very important due to its strong anti-fibrotic, vasodilatory, and cardioprotective effects. Therefore, relaxin's receptor, relaxin family peptide receptor 1 (RXFP1), is a potential target for the treatment of fibrosis and related disorders, including heart failure. WebInadequate wound healing of ocular surface injuries can lead to permanent visual impairment. The relaxin ligand-receptor system has been demonstrated to promote …
Frontiers Male Seminal Relaxin Contributes to Induction of the …
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What Is Relaxin? - Verywell Family
WebJun 24, 2002 · Relaxin, a hormone belonging to the insulin family and recently shown to act through 2 orphan G-protein receptors, has an established role in the female reproductive tract. 1–3 Known sources of relaxin are the ovary, decidua, placenta, and the prostate. 1 Three molecular forms of relaxin, H1 through H3, encoded for by separate genes, are … WebMay 27, 2014 · Recent phase III clinical trials have successfully evaluated the vasodilatory properties of serelaxin (a recombinant form of human gene-2 relaxin, which is the major stored and circulating form of relaxin in humans) in acute heart failure. 15 The antifibrotic efficacy of serelaxin, which is bioactive in mice, 13,14,16 – 19 has also been ... WebRelaxin is a polypeptide hormone produced in the human female by the corpus luteum of pregnancy and the decidua. In the male it is produced in the prostate and is present in … marielly torres