Phosphogluconolactonase
WebMay 20, 2009 · The PPP contains a series of reactions catalyzed by seven different enzymes: glucose-6-phosphate 1-dehydrogenase (G6PDH), 6-phosphogluconolactonase (6PGL), 6-phosphogluconate dehydrogenase (6PGDH), ribose-5-phophate isomerase (RPI), ribulose-5-phosphate 3-epimerase (RPE), transketolase (TK) and transaldolase (TA) … WebDec 19, 2024 · 6-phosphogluconolactone Gluconates Reactive Oxygen Species Ribulosephosphates ribulose 5-phosphate Glucosephosphate Dehydrogenase Superoxide …
Phosphogluconolactonase
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WebPartial deficiency of 6-phosphogluconolactonase (EC 3.1.1.31) of the erythrocytes was discovered as an autosomal dominant disorder. Hemolytic anemia occurred in an …
WebApr 14, 2024 · Pseudomonas cannabina pv. alisalensis (Pcal) causes bacterial blight on cabbage. We previously conducted a screening for reduced virulence using Tn5 transposon mutants and identified one of the transcriptional factors, HexR, as a potential Pcal virulence factor. However, the role of HexR in plant pathogenic Pseudomonas virulence has not … WebOct 2, 2024 · γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A Highlights • G6PD knockdown activates PP2A to neutralize activated LKB1-AMPK signaling • G6PD product 6-phosphogluconolactone (6PGL) promotes PP2A inhibition by Src •
WebNational Center for Biotechnology Information WebOct 26, 2024 · Here, by analyzing the liver cell single-cell sequencing data from HCC patients and healthy individuals, we found that 6-phosphogluconolactonase (PGLS), a cytosolic …
WebFunction Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. Catalytic activity 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+ 1 publication …
WebAug 1, 2011 · Glucose-6-phosphate dehydrogenase (G6PD) is the first enzyme of the pentose phosphate pathway, a conserved pathway responsible for producing a variety of … earth wind and fire youtube septemberWebDec 19, 2024 · The second enzyme in the oxiPPP, 6-phosphogluconolactonase (PGLS), converts 6PGL to 6-phosphogluconate (6PG). The third enzyme in the pathway, 6PGD, … earth wind and fire yaamava6-Phosphogluconolactonase (EC 3.1.1.31, 6PGL, PGLS, systematic name 6-phospho-D-glucono-1,5-lactone lactonohydrolase) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the oxidative phase of the pentose … See more 6PGL hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid has been proposed to proceed via proton transfer to the O5 ring oxygen atom, similar to xylose isomerase See more 6PGL in Homo sapiens exists as a monomer at cytosolic physiological conditions, and is composed of 258 amino acid residues with a total molecular mass of ~30 kDa. The tertiary structure of the enzyme utilizes an α/β hydrolase fold, with both parallel and … See more • 6-phosphogluconolactonase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Collard F, Collet JF, Gerin I, Veiga-da-Cunha M, Van Schaftingen E … See more 6-phosphogluconolactonase catalyzes the conversion of 6-phosphogluconolactone to 6-phosphogluconic acid, both intermediates in the oxidative phase of the pentose phosphate pathway See more Malarial parasites Plasmodium berghei and Plasmodium falciparum have been shown to express a bi-functional enzyme that exhibits both See more earth wind and fire youtube musicWebAug 2, 2006 · In this context, the crystal structure of 6-phosphogluconolactonase (6PGL) from T. brucei, the second enzyme from PPP, was determined at 2.1 Angstroms resolution. Comparison of its sequence and structure to other related proteins in the 6PGL family with a known structure (Thermotoga maritima Tm6GPL 1PBT and Vibrio cholerae Vc6PGL … earth wind and fire youtube playlistWeb6-Phosphogluconolactonase (6PGL, PGLS) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the … earth wind and flowers east hanoverWebInfobox references. 6-Phosphogluconolactone is an intermediate in the pentose phosphate pathway (PPP). In the PPP pathway, it is produced from glucose-6-phosphate by glucose … cts02 appliedWebMar 21, 2024 · The enzyme 6-phosphogluconolactonase catalyses the second step of this pathway, converting 6-phosphogluconolactone to 6-phosphogluconic acid. This enzyme has been known to have a significant involvement in growth, pathogenesis and sensitivity to oxidative stress in bacterial and protozoal pathogens. earth wind and fire youtube albums