Webb17 feb. 2024 · Currently using plink 2. I am aware that this version of plink can be used to convert VCFs into binary peds using. plink --vcf file.vcf.gz --make-bed --out out. Or something similar. I also know that in this case, plink will automatically fill the phenotype and sex columns in the bed and fam files with zeros. Webb25 aug. 2024 · 2. BED format can refer to the ".txt" file format that stores chromosomes and positions of genomic features as well as some other things like name. bed format can also refer to the plink format, which belongs to bed, bim, fam trio. The plink bed format stores all the genetic variants, but the program needs to refer to bim file for their positions.
Standard data input - PLINK 2.0 - cog-genomics.org
Webb16 maj 2016 · 用--recode命令,--out表示转化的文件的名字,本例已经命名为“filter” WebbI'm interested in converting my PED/MAP files to BED/BIM/BAM files to perform association testing. However, my PED file contains missing values coded as "-9" in addition to the affection statuses 1 (absent) and 2 (present), as illustrated below: I used the command line "plink --file FILENAME --make-bed --out FILENAME" and the conversion worked ... ehv housing search
File format reference - PLINK 2.0
Webb11 apr. 2024 · PLINK 1's preferred way to represent genotype calls. Must be accompanied by .bim and .fam files. Loaded with --bfile, and generated by --make-bed. Do not confuse this with the UCSC Genome Browser's BED format, which is totally different. (It is safe to change a PLINK 1 .bed file's extension to .pgen and use --bpfile to load it.) WebbThe --make-bed option does the same as --recode. but creates binary files; these can also be filtered, etc, as described below. In contrast, plink --file data --recode12 will recode the alleles as 1 and 2 (and the missing genotype will always be 0). Both these commands will create two new files plink.ped plink.map Webb{plink.ped} Specify .ped file--map {plink.map} Specify .map file--no-sex: PED file does not contain column 5 (sex) --no-parents: PED file does not contain columns 3,4 (parents) --no-fid: PED file does not contain column 1 (family ID) --no-pheno: PED file does not contain column 6 (phenotype) --liability: PED file does contain liability (column ... follow coding standards